When it comes to energy metabolism in the human body, one molecule present in the body whose role is highly significant is NMN. Nicotinamide mononucleotide, abbreviated as NMN, is naturally produced by the body but declines as we age.
Thanks to advancements in medicine, NMN supplements make up for the reduced NMN levels in our body. What these supplements do is boost the declining NMN level, which also leads to improved overall health and energy levels.
However, there’s much to consider when choosing the best NMN supplements for your needs. While NMN benefits abound, the NMN supplement you purchase must be high quality. Also, don’t just settle for any manufacturer, as the wellness industry is replete with several supplements by manufacturers without in-depth knowledge.
If you’re struggling with constant tiredness or your metabolic health, NMN supplements are just what you need. These supplements not only slow down the aging process but also boost your energy levels while improving your cardiovascular health.
With Wonderfeel topping our list of the best NMN supplements, here’s a guide on what NMN is, its benefits, dosage and side effects.
What is NMN?: The Deep Science Behind It
As mentioned earlier, NMN occurs naturally in the body, which also helps power it. Conversion takes place within your cells, which converts NMN to another molecule found in the body referred to as Nicotinamide Adenine Dinucleotide or NAD.
Let us break it down…
There are several molecules which occur naturally in the body, and nucleotide is one of them. Among its many roles, the nucleotide is also involved in building your DNA. NMN is a type of this molecule.
While NMN can be regarded as the “raw material,” NAD is its finished product as a result of conversion. Your body uses NAD as it’s involved in metabolism as well as energy production.
The amount of NMN available in your body determines how much NAD your body makes. If your NMN level is low, this is where the best NMN supplement comes in.
NMN Benefits
NMN is popularly known for slowing down the aging process, making you look younger for longer. But is that all it really does? There are several benefits of NMN, ranging from boosting your heart health to repairing your DNA and reducing weight gain as a result of aging.
Also, people with conditions like diabetes, insulin resistance and low energy can benefit from taking NMN supplements. However, you can only reap these benefits when the body converts the NMN into NAD.
Below are some benefits of NMN,
Enhanced metabolism
NAD aids the body’s metabolic process, which unfortunately declines as we age. A declined metabolic process leads to excessive weight gain, putting you at risk of other health conditions.
Consuming NMN supplements aids in the production of ATP or adenosine triphosphate, which converts the chemical energy present in food into fuel. The body then uses this fuel for other functions, enhancing your metabolism. With your body producing more ATP, you’ll experience improved metabolism functions.
Cognitive improvements
With aging comes a decline in energy levels as well as cognitive function. For example, having difficulty concentrating, a foggy brain, and memory loss are signs of cognitive degeneration due to aging.
What NMN does when converted to NAD is stimulate neural plasticity. When your NMN levels are low, your brain finds it difficult to convert glucose to energy. The result is a foggy and energy-depleted brain.
With the best NMN supplements, you can increase your mental sharpness while also reducing neuroinflammation. Also, consistent use of the right NMN dosage will bring about improved focus, mental clarity and memory.
Cardiovascular health
As we grow older, irregular beating of our hearts isn’t uncommon, which unfortunately leads to heart conditions and, more commonly, heart failure. The tissues in our hearts don’t regenerate, with damaged heart tissues causing heart dysfunction.
The heart works constantly, pumping blood, which contains oxygen to every organ in the body. Clogging of the heart vessels as a result of some health conditions leads to damaged heart tissues.
To protect against damaged heart tissues, supplementing with the best NMN supplements is paramount. Aside from its anti-aging properties, NMN supplements like Wonderfeel boost your cardiovascular health.
Energy production
While the best NMN supplements help your body produce ATP, which is converted to energy that cells use as fuel, the process also boosts your energy. When you supplement with NMN capsules, you can reduce fatigue, fight tiredness and boost your energy.
NMN supplements can be very beneficial if you’re an athlete and or you work out often, as improved energy increases your performance and endurance.
NMN vs. NR
Like NMN, NR, also known as nicotinamide riboside, slows the aging process. NR is a similar molecule to NMN, which, according to scientific evidence, the body converts to NMN.
Simply put, NR is converted to NNM and then NAD for use by the body. Many aging specialists like Dr. David Sinclair have the belief that NMN is better than NR. Here are some differences between NMN and NR.
- NMN has more impressive results than NR, according to several clinical studies. Compared to NR, NMN offers better results for many age-related illnesses and symptoms.
- NMN is closer to NAD than NR as NR has to be converted to NMN first before becoming NAD. Scientists believe that going further down the NAD pathway equals an increase in effectiveness.
- Unlike NMN, which is stable in the bloodstream, NR is unstable, quickly degrading to vitamin B3.
When you take NR orally, it gets broken down in the gut to Nicotinamide, a vitamin B3 form. The little NR the gut absorbs goes through the liver, which also breaks it down to nicotinamide and vitamin B3. Basically, taking NR supplements is the same as taking expensive vitamin B3.
Top 5 Best NMN Supplements
Supporting your well-being at a cellular level is essential for living a long and healthy life, and it is not uncommon to find many people turn to supplements for this.
As interest in NMN continues to grow, numerous brands have developed NMN supplements, each claiming to be the best. However, here’s a dive into the best five you can get in the market, offering outstanding and long-lasting results.
Wonderfeel Younger™
First on our list of the best NMN supplements is none other than the Wonderfeel Youngr™. A leading company out of San Fransisco, Wonderfeel offers the most potent NAD precursor formula. This unique formula, which is backed by clinical trials, features a 900mg dose of NMN.
Wonderfeel is engineered by prominent Harvard professor and scientist Andrew Salzman. With over 50 patents and almost 30 years in cellular health and NAD, Wonderfeel’s patented formula has unique ingredients like hydroxytyrosol, which comes from olive fruit and, Ergo from mushrooms. That’s not all; Wonderfeel also features 100% daily Vitamin D3 and resveratrol.
What’s In It
Wonderfeel Youngr™ contains
- Nicotinamide Mononucleotide 900 mg
- Ergothioneine 4 mg
- Resveratrol 100 mg
- Hydroxytyrosol 20 mg
- Vitamin D3 20 mcg
Here’s a breakdown of the ingredients in Wonderfeel’s Youngr™ and their benefits
Ergothioneine (ERGO)
Known as the longevity vitamin, ergothioneine, also called ergo, is found in mushrooms and acts as a therapeutic agent. When ergo accumulates in the body where it’s needed, it can stay there for up to four weeks, showing an impressive retention level.
With scientific evidence showing the benefits of ergo, one benefit that stands out is the effect on cognitive functions as it aids the brain from aging. That’s not all; the cardiovascular system benefits from ergo, which strengthens it.
Hydroxytyrosol
Another ingredient in Wonderfeel is Hydroxytyrosol, which has anti-inflammatory, antitumour and metabolic properties. Gotten from ripened and unprocessed olives, hydroxytyrosol is one of the best-known and most potent antioxidants.
In addition, hydroxytyrosol is one of olive oil’s key ingredients that gives the Mediterranean diet its fame for being extremely healthy.
Vitamin D3
One Vitamin the body requires for insulin production and immune function is Vitamin D3. Also regarded as cholecalciferol, Vitamin D3 is made by the skin when you expose it to sunlight. With fewer people taking morning walks and spending more time indoors, we rob ourselves of the numerous benefits of Vitamin D3. Also, the use of sunscreen and the scarcity of sunlight in certain regions can cause the benefits of Vitamin D3 from sunlight to elude us.
One benefit of Vitamin D3, aside from aiding immune function, is generating the gut’s stem cells, which improves our overall health. With the best NMN supplement, Wonderfeel, you’re sure to get 20mcg of Vitamin D3, the recommended dosage according to the FDA.
Resveratrol
Resveratrol, which works closely with NMN, functions as a sirtuin activator in the Wonderfeel NMN supplement. The functions of sirtuins in the body include regulation of metabolism, cell survival, aging processes and stress responses.
According to studies, resveratrol in lower doses functions as an anti-apoptotic agent, which aids the increase of cell survival proteins. Resveratrol is essential when it comes to slowing down aging and increasing your health span. It’s not uncommon to find the mitochondria damaging as we age. Thanks to Wonderfeel NMN 100mg capsules, which contain 100mg of resveratrol, you can prevent metabolic diseases and boost mitochondrial activity.
Benefits of Wonderfeel
The Wonderfeel NMN supplement, which contains NMN + resveratrol, offers several benefits, including increased and improved sleep quality. Here are some reasons to get the Wonderfeel NMN supplement.
- 900mg NMN, a high dose supported by the latest and most comprehensive human clinical study.
- Emergent antioxidants and sirtuin activation is a multi-targeted approach to defend and slow biological aging.
- Developed by Andrew Salzman, a Harvard MD and leading scientist.
- The best value, and available with great subscription discounts
- Wonderful customer reviews about higher energy levels and better sleep quality
To use the Wondefeel NMN supplements, simply take two 450mg capsules in the morning alongside a meal rich in fat. With regular consumption, you’ll notice a difference in not just your body but the quality of your life when you use the Youngr™.
While some people report noticeable changes in as little as a week, others may find their results begin to show some weeks after. What’s essential is consistent use and tracking.
Human People NMN Pure Supplement
Making it on our list of the best NMN supplements is the Human People NMN Pure supplement. Suitable for vegetarians and vegans, Human People NMN Pure supplement boosts energy production for both your mental and physical health. Also, it protects against aging, increases your longevity and improves your sleep.
However, unlike Wonderfeel, Human People NMN Pure supplement contains 99.5% pure B-NMN 500mg. The Wonderfeel Youngr™ contains 900mg of NMN. To use, take one capsule of 500mg NMN daily, which is absorbed into the body in about 20 minutes, boosting your energy levels in a short time.
Benefits of Human People NMN Pure Supplement
Here are some benefits of Human People NMN supplement
- Increased NAD+ levels
- Cellular energy and metabolism
- DNA repair and maintenance
- Sirtuin activation
- Anti-aging effects
- Longevity benefits
Pharma Aesthetics NMN Supplements
If you’re vegan or a vegetarian, you’d love Pharma Aesthetics NMN supplements. This GMO-free supplement contains pure NMN, which is known to prevent illnesses due to aging.
One outstanding feature of Pharma Aesthetics NMN supplements is that they are available in capsule and powder forms. This versatility allows you to easily incorporate the supplements into your routine.
The capsules come in 125mg to be consumed twice to four times daily. It’s essential that you take the first capsule on an empty stomach alongside a sirtuin activator like curcumin and resveratrol. Also, the powder NMN supplement should be placed under your tongue until it dissolves for optimal absorption.
Benefits of Pharma Aesthetics NMN supplements
Below are some of the benefits of using Pharma Aesthetics NMN supplements.
- Aids in the treatment of metabolic illnesses
- Strengthens your immune system
- Reduces neurodegeneration rate
- Enhances and regulates cardiovascular activities
Time Health NMN
Proven to increase NAD+, Time Health UTHEVER® NMN supplement can be taken sublingually in its powder form or swallowed as a capsule. Thanks to its enteric coating, this supplement has high absorption levels, delivering the NMN directly into your gut and increasing its effectiveness.
Whether you consume the Time Health UTHEVER® NMN supplement sublingually or orally, both administration methods bypass your stomach in a bid to prevent the stomach acid from acting on it.
Benefits of Time Health UTHEVER® NMN supplement
One reason you’ll love the Time Health NMN supplements is their bioavailability. 100% fillers and binders free, this supplement is known for its ultra-pure 99% NMN ingredient and positive reviews. Here are some of its top benefits
- Contains pure NMN
- Third-party tested
- Stable at room temperature
- Increases NAD+ levels
- Available in powder and capsule
Fivescore Ultra High Purity NMN Supplements
Unlike many NMN supplements, Fivescore Ultra High Purity NMN supplements use a more stable next-generation NMN product, which ensures the final supplement is pure and more stable. The stability translates to an extended shelf life, making this NMN supplement highly loved.
Fivescore NMN supplements aren’t affected when in an unstable temperature as they were designed to remain stable at ambient temperatures. This feature is unique as many NMN supplements in the market are unstable at room temperature, even further degrading when not in a temperature-controlled environment.
Benefits of Fivescore Ultra High Purity NMN supplement
This supplement has several benefits, from using next-generation NMN product to being stable even at unfavourable temperatures. They are,
- Packaged in a biodegradable bottle, making it safe for the environment
- Free from binders, additives and fillers
- Ideal for vegans
- Enteric-coated, making the capsules more absorbable and effective
- It contains pure 99% NMN
David Sinclair’s NMN Research
It’s almost impossible to talk about NMN research without mentioning Dr. David Sinclair. Professor at Harvard, Dr. David Sinclair, has spent decades researching aging, especially the role sirtuins play in aging.
Dr. Sinclair’s research was focused on certain substances capable of improving sirtuins activity, like NR, NMN, pterostilbene and resveratrol. According to his research, these substances have the potential to improve epigenomic and DNA stability while also mitigating aging. However, Dr David Sinclair found NMN to have the most potential out of all these substances.
In his book Lifespan, Dr. David Sinclair opens up about his NMN supplement routing, stating that he takes NMN supplements every day. According to the book, he incorporates NMN into the yogurt he has for breakfast, as NMN is bioavailable orally.
In addition, Dr. David Sinclair stated he consumes NMN in a single dose of 1000mg. It’s interesting to note that although NR and NMN bear similarities, Dr. David Sinclair takes NMN and not NR. There are speculations that he’s of the opinion NMN offers more benefits than NR.
Aside from being a pioneer in the research of NMN, Dr. David Sinclair is also renowned for how he views aging. According to the Harvard professor, he believes aging can’t only be slowed down but can also be partially reversed. By this, it would mean older adults can be made younger again.
NMN Side Effects and Safety
If you want to increase your cellular levels of NAD, the best NMN supplements are ideal. Not only are NMN supplements well tolerated, but according to several studies on both animals and humans, they have been proven to have little to no side effects.
However, some individuals may find that they experience mild gastrointestinal issues such as nausea, diarrhea, or stomach discomfort. Dr. David Sinclair also stated that he experiences little stomach discomfort. However, for the results he gets, the occasional stomach upset is worth it.
Here are some safety precautions to observe when using NMN supplements,
Pregnancy and breast-feeding: As a precaution, pregnant and breastfeeding individuals should avoid NMN supplementation due to the limited research on its safety in these populations.
- Underlying medical conditions: If you have pre-existing medical conditions, always consult a healthcare professional before using NMN supplements. Your healthcare professional can help determine if NMN is appropriate for you and suggest an appropriate dosage based on your health status.
- Use only the best NMN supplements: Choose reputable and trustworthy suppliers or manufacturers known for producing high-quality, pure NMN supplements like Wonderfeel. Wonderfeel NMN supplement is third-party tested, has quality certifications, and is transparent in sourcing and production, ensuring its purity and potency.
- Healthy lifestyle practices: To maximize the benefits of NMN supplements, it’s essential to complement NMN supplementation with a healthy lifestyle. This includes a balanced diet and regular exercise to support your overall well-being.
NMN Dosage
Typically, you’d find 500mg and 100mg NMN supplements, like the Wonderfeel Youngr™ NMN supplements. The doses can be split into a maximum of six, depending on the manufacturer. It’s always essential to go through the manufacturer’s label and read the dosage guidelines before taking the supplement.
Although there are practically no side effects of NMN supplements, there are no standard doses of NMN. NMN experts like Wonderfeel’s head scientist, Dr. Salzman and Dr. Sinclair, are of the belief that higher doses of NMN are more beneficial, producing more results.
According to a 2022 clinical study, results of placebo, 900mg, 600mg and 300mg doses showed that the 900ng group had the greatest efficacy. Additionally, it’s common to find supplement manufacturers recommend supplements does according to their observations and research. For instance, they recommend higher doses for a person with a heavier weight.
To Wrap It Up
Thanks to advancements in medicine, NMN supplements present a promising avenue in the pursuit of enhanced health and potential longevity. Extensive research has shed light on the critical role of NMN in cellular metabolism, energy production, DNA repair, and overall aging processes.
In choosing the best NMN supplement, prioritizing quality and transparency in sourcing and third-party testing is paramount. Reputable brands like Wonderfeel, committed to providing pure, high-quality NMN supplements without harmful additives or contaminants, should be the go-to choice.
In this article, we’ve explored the best NMN supplements, making it easy for you to incorporate this fantastic supplement into your routine. Also, we answer questions on what NMN is, its benefits, dosage and potential side effects.
Living a long and healthy life requires you to invest in your health. With quality products from Wonderfeel, check out their website.
